Python is an interpreted high-level programming language for general-purpose programming. Python has a design philosophy that emphasizes code readability, notably using significant whitespace. It provides constructs that enable clear programming on both small and large scales. Python features a dynamic type system and automatic memory management. It supports multiple programming paradigms, including object-oriented, imperative, functional, and procedural, and has a large and comprehensive standard library. This book has become successful because of our special interest and Knowledge in emerging technology. Our intention is to make this work to reach the students and make them upgrade their technical knowledge in the future. This book covers all topics of Problem Solving and Python Programming syllabus offered by Anna University. It helps the students to understand the concepts in Simple and to-the-point explanations using numerous programming examples. It also provides detailed coverage of fundamental constructs, strings, file handling, classes, and exception handling in Python.